We are building Heroes of Steel, a squad-based RPG, using Spine. It's all top-down animation.
I just posted a YouTube video showing off how we are using it to make individual character appearance very modular:
http://www.youtube.com/watch?v=F31NBWimlls
We happened across the Spine KickStarter right when we were successfully funding our own KickStarter and were really excited to see Cocos2dx on the runtime list and joined as backers!
Great work team!